toluenesulfonic acid การใช้

• A common example is toluenesulfonic acid ( tosylic acid ).
• A common example is p-toluenesulfonic acid ( tosylic acid ).
• This reaction has been catalyzed by trifluoroacetic acid, toluenesulfonic acid, iodine, and Lewis acids.
• Sulfonation occurs on the side chains, not on the aromatic ring like in p-toluenesulfonic acid.
• European and Japanese companies use the reaction of " p "-toluenesulfonic acid or methanesulfonic acid.
• Br鴑sted acids such as HCl, H 2 SO 4, polyphosphoric acid and p-toluenesulfonic acid have been used successfully.
• Bronsted acids such as HCl, H 2 SO 4, polyphosphoric acid and p-toluenesulfonic acid have been used successfully.
• Because this lone pair is not part of the aromatic ring, pyridine is a " p "-toluenesulfonic acid.
• In 2005, researchers produced pyrogallol [ 4 ] arene simply by mixing a " p "-toluenesulfonic acid, in a mortar and pestle.
• Methanesulfonic acid is convenient for industrial applications because it is liquid at ambient temperature, while the closely related " p "-toluenesulfonic acid ( PTSA ) is solid.
• The court set forth that the replacement of the claimed p-Toluenesulfonic acid with pyridine / water constituted basic knowledge taught during the first years of an undergraduate course in organic chemistry.
• The reaction is catalyzed by Lewis acids such as tin tetrachloride and scandium ( III ) triflate and Br鴑sted acids such as " p "-toluenesulfonic acid, perchloric acid, amberlite and iodine.
• Upon the addition of a base such as sodium hydroxide or potassium hydroxide, an elimination reaction occurs to produce diazomethane as well as p-toluenesulfonic acid as a side product, according to the following mechanism:
• A green chemistry procedure was recently developed using solvent-free conditions : resorcinol, an aldehyde, and " p "-toluenesulfonic acid are ground together in a mortar and pestle at low temperature.
• On the other hand, most organic acids are very soluble in organic solvents . " p "-Toluenesulfonic acid is a comparatively strong acid used in organic chemistry often because it is able to dissolve in the organic reaction solvent.
• The construction of the eight-carbon cubane framework begins when 2-bromocyclopentadienone undergoes a spontaneous " p "-toluenesulfonic acid in benzene; one acetal is then selectively deprotected with aqueous hydrochloric acid to "'3 " '.
• In solution-phase synthesis, acidic conditions are essential; formic acid, acetic acid, and propionic acid are typical reaction solvents, or " p "-toluenesulfonic acid or various Lewis acids can be used with a non-acidic solvent.
• Removal of the silyl protecting group with p-toluenesulfonic acid to alcohol "'4b "'and ring-closure by azeotropic distillation returns the compound to lactone "'5 "'( direct alkylation of 1 met with undisclosed problems ).